IRGACARE^®† MP-Coated Plus Sutures

IRGACARE^® MP is a safe and effective
antimicrobial agent

The safety of IRGACARE^® MP

• IRGACARE^® MP-coated sutures were found to be nontoxic, nonirritating, noncarcinogenic, and nonteratogenic (does not cause fetal malformation) in in vivo and in pre clinical studies¹
• Triclosan, the generic form of IRGACARE^® MP, has been safely used in a wide variety of over-the-counter healthcare and consumer products for over 30 years¹

IRGACARE^® MP does not contribute to the antibiotic burden

• IRGACARE^® MP is an antiseptic and has no proven clinical connection with antibiotic resistance^2,3
• By inhibiting the growth of pathogenic bacteria most associated with SSIs, IRGACARE^® MP addresses a risk factor associated with SSI²

The minimal environmental impact of IRGACARE^® MP-coated Plus Sutures

• The potential daily absorption of triclosan from common consumer products is estimated to be 29 times greater than that of the average exposure from triclosan in implanted Coated VICRYL* Plus Antibacterial (polyglactin 910) Suture in a typical case¹

• IRGACARE^® MP is rapidly metabolized, biodegraded, and excreted through feces and urine in a neutralized, inactive form, and therefore does not accumulate in the body¹
• Based on a conservative assessment of estimates from the United States Environmental Protection Agency, the average environmental exposure to IRGACARE^® MP residue produced by Coated VICRYL Plus Sutures is extremely limited¹

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